Amateur MMA Fighter, 21, Dies from Rare Muscle Condition After Intense Training

Sarah Johnson
March 20, 2025
Jake Sendler, a 21-year-old amateur MMA fighter from Australia, tragically lost his life on March 13 due to complications from rhabdomyolysis, a rare and life-threatening muscle condition triggered by intense exercise. His passing came just 11 days after he was hospitalized following a fight.
According to his mother, Sharone Sendler, Jake had been experiencing muscle soreness and noticed discoloration in his urine leading up to his amateur fight on March 2. He brushed off the symptoms, attributing them to dehydration from rigorous training. Despite these warning signs, he was medically cleared to compete in the bout, where he fought valiantly for three full rounds. However, after the fight, he had to be assisted out of the ring, and an ambulance was called to rush him to the hospital.
Doctors diagnosed Jake with rhabdomyolysis, a condition that causes muscle fibers to break down and release harmful toxins into the bloodstream, potentially leading to kidney damage and multi-organ failure. Sharone revealed that her son underwent multiple surgeries, but the damage to his body was irreversible. "When they opened him up again during an emergency surgery, the doctors saw too much tissue had died. There was nothing more they could do," she said. In a heartbreaking farewell, she told Jake, "It’s OK, baby, you can rest now," before he passed away.
The fight organizer, Road to HEX, expressed their condolences in a statement, calling Jake's dedication and spirit "deeply missed." They extended their sympathies to his family, friends, and training community at Mat Masters Academy.
The Cleveland Clinic defines rhabdomyolysis as a rare condition caused by factors such as overexertion, trauma, medications, or underlying health conditions. Jake’s case appears to have been exacerbated by his intense training regimen and the demands of preparing for his fight. His final moments in the ring demonstrated remarkable determination, despite his body already showing signs of critical failure.
A GoFundMe campaign has been launched in Jake’s memory to raise awareness about rhabdomyolysis and to assist his family with funeral expenses. The campaign highlighted Jake’s fighting spirit, noting that he "pushed through worsening symptoms, training and coaching despite his body shutting down." Tragically, his condition deteriorated rapidly after the fight, leading to the most severe case of rhabdomyolysis his doctors had ever encountered.
This heartbreaking story also brings attention to other cases of rhabdomyolysis in the sports world. In September, 12 members of the Tufts University men’s lacrosse team were diagnosed with the condition after a workout led by a Navy SEAL-trained graduate. The incident underscores the importance of recognizing the signs of overexertion and seeking immediate medical attention.
Editor's Comments
This story is both tragic and cautionary, a reminder of the fine line between pushing limits and pushing too far. Jake's determination is admirable, but his story highlights the need for athletes to listen to their bodies and for medical professionals to take early symptoms seriously. The fact that he sold 60 tickets for his friends and family to watch him fight makes the loss even more poignant—he truly fought with his whole heart. Awareness about rhabdomyolysis could save lives, and that’s one small solace in this heartbreaking tale.
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